FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

rixosome complex

ID (Ontology)

GO:0120330 (Gene Ontology)

Definition

A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.[ PubMed:32491985 PubMed:35355014 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
rixosome complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| rixosome complex

Spanning Tree (Parents/Children)

  endonuclease complex
   |__endoribonuclease complex
       |__rixosome complex  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	endoribonuclease complex
Part of
Synonyms & Secondary IDs
Synonyms
	"rix1 complex" NARROW
Secondary IDs

External Crossreferences & Linkouts