FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term rixosome complex ID (Ontology) GO:0120330 (Gene Ontology)
Definition A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.[ PubMed:32491985 PubMed:35355014 ]
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       1
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 rixosome complex (all annotations which use CV term, excluding "NOT" statements)       1
     part_of | rixosome complex       1
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  endonuclease complex
   |__endoribonuclease complex
       |__rixosome complex  1 rec.
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Is a endoribonuclease complex
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  • "rix1 complex" NARROW
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