FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term NAE1-UBA3 complex ID (Ontology) GO:0120500 (Gene Ontology)
Definition A heterodimeric E1 complex that activates the ubiquitin-like protein NEDD8. In humans the subunits are NAE1 (also known as APPBP1) and UBA3.[ PubMed:12740388 PubMed:21931660 ]
Also Known As"APPBP1-UBA3 complex" ; "NAE" ; "NEDD8 activating enzyme"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 NAE1-UBA3 complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | NAE1-UBA3 complex
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  protein-containing complex
   |__catalytic complex
       |__NAE1-UBA3 complex  2 rec.
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Is a catalytic complex
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Synonyms
  • "APPBP1-UBA3 complex" EXACT
    "NAE" EXACT
    "NEDD8 activating enzyme" EXACT
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