FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term EXT1-EXT2 complex ID (Ontology) GO:0120504 (Gene Ontology)
Definition A heterodimeric complex capable of glycosyltransferase activity required for the elongation of heparan sulfate chains. In humans, the complex consists of EXT1 and EXT2. In Drosophila, the complex consists of ttv and sotv.[ PubMed:14998928 PubMed:36402845 PubMed:36593275 ]
Also Known As "exostosin complex" ; "EXT1-EXT2 heparan sulfate biosynthesis complex"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       2
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Relevant FlyBase reports
 Gene Groups Genes
 EXT1-EXT2 complex (all annotations which use CV term, excluding "NOT" statements)       1      2
     part_of | EXT1-EXT2 complex       --       2
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  catalytic complex
   |__transferase complex
       |__EXT1-EXT2 complex  3 rec.
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Is a transferase complex
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Synonyms
  • "exostosin complex" EXACT
    "EXT1-EXT2 heparan sulfate biosynthesis complex" EXACT
Secondary IDs
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