FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term tRNA-guanine transglycosylase complex ID (Ontology) GO:0120507 (Gene Ontology)
Definition A protein complex that catalyzes the base-exchange of a guanine residue with queuine at the wobble position of the anticodon of tRNAs. The eukaryotic tRNA-guanine transglycosylase exists as a heterodimer of a catalytic subunit (QTRT1 in humans) and an accessory subunit (QTRT2 in humans), whereas the bacterial enzyme is homodimeric.[ PubMed:20354154 PubMed:38181786 ]
Also Known As"queuine tRNA-ribosyltransferase complex" ; "TGT"
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 tRNA-guanine transglycosylase complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | tRNA-guanine transglycosylase complex       --
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  catalytic complex
   |__transferase complex
       |__tRNA-guanine transglycosylase complex  3 rec.
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Is a transferase complex
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Synonyms
  • "queuine tRNA-ribosyltransferase complex" EXACT
    "TGT" EXACT
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