FB2026_03 , released September 17, 2026
CV Term Report
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Term fatty acid-CoA ligase activity ID (Ontology) GO:0120515 (Gene Ontology)
Definition Catalysis of the reaction: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate.
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 fatty acid-CoA ligase activity (all annotations which use CV term, excluding "NOT" statements)
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acid-thiol ligase activity
 |__fatty acid ligase activity__
 |__CoA-ligase activity_________|
ATP-dependent activity          |
 |__fatty acid ligase activity__|
                                fatty acid-CoA ligase activity  25 rec.
                                 |__long-chain fatty acid-CoA ligase activity 21 rec.
                                 |   |__arachidonate-CoA ligase activity
                                 |   |__myristoyl-CoA ligase activity
                                 |   |__oleoyl-CoA ligase activity
                                 |   |__palmitoyl-CoA ligase activity 1 rec.
                                 |__medium-chain fatty acid-CoA ligase activity 1 rec.
                                 |   |__decanoate-CoA ligase activity
                                 |__short-chain fatty acid-CoA ligase activity 1 rec.
                                 |   |__2-methylbutanoate-CoA ligase activity
                                 |   |__propionate-CoA ligase activity 1 rec.
                                 |__very long-chain fatty acid-CoA ligase activity 2 rec.
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Is a fatty acid ligase activity
CoA-ligase activity
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MetaCyc:BUTYRATE--COA-LIGASE-RXN
RHEA:38883
RHEA:44004
RHEA:44196