FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term free fatty acid 2-hydroxylase activity ID (Ontology) GO:0120520 (Gene Ontology)
Definition Catalysis of the reaction: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O. Note that the substrate is a free fatty acid, not a fatty acyl chain within a sphingolipid.
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Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Genes
 free fatty acid 2-hydroxylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | free fatty acid 2-hydroxylase activity       1
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  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
   |__fatty acid 2-hydroxylase activity
       |__free fatty acid 2-hydroxylase activity  1 rec.
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Is a fatty acid 2-hydroxylase activity
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RHEA:38855