FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity

ID (Ontology)

GO:0120521 (Gene Ontology)

Definition

Catalysis of the reaction: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O.

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity (all annotations which use CV term, excluding "NOT" statements)
enables \| 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity

Spanning Tree (Parents/Children)

  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
   |__fatty acid 2-hydroxylase activity
       |__4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	fatty acid 2-hydroxylase activity
Part of
Synonyms & Secondary IDs
Synonyms

Secondary IDs

External Crossreferences & Linkouts
	EC:1.14.18.6 MetaCyc:RXN3O-4042 RHEA:46520 RHEA:64532