FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term glycosaminoglycan-protein linkage region biosynthetic process ID (Ontology) GO:0120532 (Gene Ontology)
Definition The formation of a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate) on specific serine residues of a core protein, on to which dermatan sulfate, chondroitin sulfate, heparan sulfate or heparin glycosaminoglycans may be assembled to synthesise the corresponding proteoglycan.
Also Known As"Glycosaminoglycan biosynthesis, linkage tetrasaccharide" ; "glycosaminoglycan-protein linkage region biosynthesis"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
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 glycosaminoglycan-protein linkage region biosynthetic process (all annotations which use CV term, excluding "NOT" statements)
     involved_in | glycosaminoglycan-protein linkage region biosynthetic process
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protein O-linked glycosylation
 |__protein O-linked glycosylation via xylose______________
proteoglycan biosynthetic process                          |
 |__heparan sulfate proteoglycan biosynthetic process______|
 |__chondroitin sulfate proteoglycan biosynthetic process__|
 |__dermatan sulfate proteoglycan biosynthetic process_____|
heparan sulfate proteoglycan metabolic process             |
 |__heparan sulfate proteoglycan biosynthetic process______|
heparin proteoglycan metabolic process                     |
 |__heparin proteoglycan biosynthetic process______________|
chondroitin sulfate proteoglycan metabolic process         |
 |__chondroitin sulfate proteoglycan biosynthetic process__|
dermatan sulfate proteoglycan metabolic process            |
 |__dermatan sulfate proteoglycan biosynthetic process_____|
protein O-linked glycosylation via xylose                  |
 |__heparan sulfate proteoglycan biosynthetic process______|
 |__heparin proteoglycan biosynthetic process______________|
 |__chondroitin sulfate proteoglycan biosynthetic process__|
 |__dermatan sulfate proteoglycan biosynthetic process_____|
                                                           glycosaminoglycan-protein linkage region biosynthetic process  4 rec.
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Is a protein O-linked glycosylation via xylose
Part of heparan sulfate proteoglycan biosynthetic process
heparin proteoglycan biosynthetic process
chondroitin sulfate proteoglycan biosynthetic process
dermatan sulfate proteoglycan biosynthetic process
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Synonyms
  • "Glycosaminoglycan biosynthesis, linkage tetrasaccharide" EXACT
    "glycosaminoglycan-protein linkage region biosynthesis" EXACT
Secondary IDs
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MetaCyc:PWY-6557
Reactome:R-HSA-1971475 "Glycosaminoglycan-protein linkage region biosynthesis"