FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term mechanosensitive monoatomic cation channel activity ID (Ontology) GO:0140135 (Gene Ontology)
Definition Enables the transmembrane transfer of a monoatomic cation by a channel that opens in response to a mechanical stress.[ PubMed:22343900 ]
Also Known As "mechanically-gated cation channel activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       8
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 mechanosensitive monoatomic cation channel activity (all annotations which use CV term, excluding "NOT" statements)       4      8
     enables | mechanosensitive monoatomic cation channel activity       --       8
Spanning Tree (Parents/Children)
Only view relationship: 
monoatomic ion channel activity
 |__monoatomic cation channel activity________________
 |__mechanosensitive monoatomic ion channel activity__|
monoatomic cation transmembrane transporter activity  |
 |__monoatomic cation channel activity________________|
gated channel activity                                |
 |__mechanosensitive monoatomic ion channel activity__|
                                                      mechanosensitive monoatomic cation channel activity  14 rec.
                                                       |__mechanosensitive potassium channel activity
                                                       |__mechanosensitive voltage-gated sodium channel activity
                                                       |__stretch-activated, monoatomic cation-selective, calcium channel activity 2 rec.
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Is a monoatomic cation channel activity
mechanosensitive monoatomic ion channel activity
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Synonyms
  • "mechanically-gated cation channel activity" EXACT
    "mechanosensitive cation channel activity" BROAD
Secondary IDs
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Reactome:R-HSA-9659380 "Mechanoelectrical transduction (MET) channel transports cations from the extracellular region into the cytosol of stereocilia of inner hair cell"
Reactome:R-HSA-9663363 "Mechanoelectrical transduction (MET) channel transports cations into the cytosol of stereocilia of cochlear outer hair cell"
Reactome:R-HSA-9855089 "PIEZO1 trimer passively transports cations across the plasma membrane according to their electrochemical gradients"