FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term cargo adaptor activity ID (Ontology) GO:0140312 (Gene Ontology)
Definition Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.[ PubMed:25795254 ]
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      10
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 cargo adaptor activity (all annotations which use CV term, excluding "NOT" statements)      10
     contributes_to | cargo adaptor activity       2
     enables | cargo adaptor activity       8
Spanning Tree (Parents/Children)
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  molecular adaptor activity
   |__protein-macromolecule adaptor activity
       |__cargo adaptor activity  23 rec.
           |__clathrin-cargo adaptor activity 14 rec.
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Is a protein-macromolecule adaptor activity
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Synonyms
  • "endocytic adaptor activity" NARROW
Secondary IDs
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Reactome:R-HSA-203565 "eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP"
Reactome:R-HSA-203662 "eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2"