FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term ABC-type transporter activity ID (Ontology) GO:0140359 (Gene Ontology)
Definition Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.[ PubMed:26517899 ]
Also Known As "ABC transporter" ; "ABC-type efflux permease activity" ; "ABC-type efflux porter activity" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      52
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 ABC-type transporter activity (all annotations which use CV term, excluding "NOT" statements)       7     52
     enables | ABC-type transporter activity       --      52
Spanning Tree (Parents/Children)
Only view relationship: 
primary active transmembrane transporter activity__
ATP-dependent activity_____________________________|
                                                   ATPase-coupled transmembrane transporter activity
                                                    |__ABC-type transporter activity  59 rec.
                                                        |__ABC-type 3',5'-cyclic GMP transmembrane transporter activity 1 rec.
                                                        |__ABC-type alkanesulfonate transporter transporter activity
                                                        |   |__ABC-type taurine transporter transporter activity
                                                        |__ABC-type amino acid transporter activity
                                                        |   |__ABC-type cysteine transporter activity
                                                        |   |__ABC-type D-methionine transporter activity
                                                        |   |__ATPase-coupled nonpolar-amino acid transporter activity
                                                        |   |__ATPase-coupled polar amino acid-transporter activity(+)
                                                        |__ABC-type azole transporter activity
                                                        |   |__ABC-type thiamine transporter activity
                                                        |__ABC-type betaine transporter activity
                                                        |__ABC-type bile acid transporter activity
                                                        |__ABC-type cadmium transporter activity
                                                        |__ABC-type capsular-polysaccharide transporter activity
                                                        |__ABC-type carbohydrate transporter activity
                                                        |   |__ABC-type beta-glucan transporter activity
                                                        |   |__ABC-type monosaccharide transporter activity(+)
                                                        |   |__ABC-type oligosaccharide transporter activity(+)
                                                        |__ABC-type choline transporter activity
                                                        |__ABC-type doxorubicin transporter activity
                                                        |__ABC-type fatty-acyl-CoA transporter activity 1 rec.
                                                        |__ABC-type ferric hydroxamate transporter activity
                                                        |__ABC-type ferric iron transporter activity
                                                        |__ABC-type ferric-enterobactin transporter activity
                                                        |__ABC-type glutathione S-conjugate transporter activity
                                                        |__ABC-type glycerol-3-phosphate transporter activity
                                                        |__ABC-type guanine transporter activity 1 rec.
                                                        |__ABC-type heme transporter activity 3 rec.
                                                        |__ABC-type indole transporter activity
                                                        |__ABC-type iron-sulfur cluster transporter activity 1 rec.
                                                        |__ABC-type manganese transporter activity
                                                        |__ABC-type molybdate transporter activity
                                                        |__ABC-type nickel transporter activity
                                                        |__ABC-type nitrate transporter activity
                                                        |__ABC-type oligopeptide transporter activity 1 rec.
                                                        |__ABC-type peptide transporter activity
                                                        |   |__ABC-type peptide antigen transporter activity
                                                        |__ABC-type phosphonate transporter activity
                                                        |__ABC-type phytochelatin transporter activity
                                                        |__ABC-type polyamine transporter activity
                                                        |   |__ABC-type putrescine transporter activity
                                                        |__ABC-type protein transporter activity
                                                        |__ABC-type quaternary ammonium compound transporting activity
                                                        |   |__ABC-type glycine betaine transporter activity
                                                        |__ABC-type sodium transporter activity
                                                        |__ABC-type sterol transporter activity
                                                        |__ABC-type sulfate transporter activity
                                                        |__ABC-type teichoic acid transporter activity
                                                        |__ABC-type thiosulfate transporter activity
                                                        |__ABC-type tungstate transporter activity
                                                        |__ABC-type vitamin B12 transporter activity
                                                        |__ABC-type xenobiotic transporter activity 5 rec.
                                                        |   |__ABC-type bacteriocin transporter activity
                                                        |__ABC-type zinc transporter activity
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Is a ATPase-coupled transmembrane transporter activity
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Synonyms
  • "ABC transporter" EXACT
    "ABC-type efflux permease activity" EXACT
    "ABC-type efflux porter activity" EXACT
    "ABC-type transmembrane transporter activity" EXACT
    "ABC-type uptake permease activity" EXACT
    "ATP binding cassette transporter" EXACT
    "ATP-binding cassette (ABC) transporter activity" EXACT
    "ATP-binding cassette transporter" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-266070 "LTC4 is exported from the cytosol by ABCC1"
Reactome:R-HSA-429157 "ABCC4 accumulation of dense granule contents"
Reactome:R-HSA-5362459 "VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol"
Reactome:R-HSA-5387389 "Hh processing variants are translocated to the cytosol in a VCP-dependent manner"
Reactome:R-HSA-9661405 "ABCC1 transports BIL from cytosol to extracellular region (blood)"
Reactome:R-HSA-9750656 "ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells"
TC:3.A.1
Wikipedia:ATP-binding_cassette_transporter