FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term histone reader activity ID (Ontology) GO:0140566 (Gene Ontology)
Definition A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery.[ PubMed:11498575 PubMed:25688442 PubMed:31082667 PubMed:34726351 ]
Also Known As "histone reader"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION      12
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 histone reader activity (all annotations which use CV term, excluding "NOT" statements)      12
     enables | histone reader activity      12
Spanning Tree (Parents/Children)
Only view relationship: 
  protein-macromolecule adaptor activity
   |__chromatin-protein adaptor activity
       |__histone reader activity  28 rec.
           |__histone H1 reader activity
           |   |__histone H1K26me1 reader activity
           |   |__histone H1K26me2 reader activity
           |__histone H2A reader activity
           |   |__histone H2AK5ac reader activity
           |   |__histone H2AK15ac reader activity
           |   |__histone H2AK15ub reader activity
           |   |__histone H2AS139pho reader activity
           |   |__histone H2AT120pho reader activity
           |__histone H2B reader activity
           |__histone H3 reader activity 13 rec.
           |   |__histone H3K4me1 reader activity 2 rec.
           |   |__histone H3K4me3 reader activity 5 rec.
           |   |__histone H3K9ac reader activity
           |   |__histone H3K9cr reader activity
           |   |__histone H3K9me2/3 reader activity 4 rec.
           |   |__histone H3K14ac reader activity 1 rec.
           |   |__histone H3K14ub reader activity
           |   |__histone H3K18ac reader activity
           |   |__histone H3K18cr reader activity
           |   |__histone H3K18ub reader activity
           |   |__histone H3K23ac reader activity
           |   |__histone H3K23ub reader activity
           |   |__histone H3K27ac reader activity
           |   |__histone H3K27cr reader activity
           |   |__histone H3K27me3 reader activity
           |   |__histone H3K36me3 reader activity 5 rec.
           |   |__histone H3K56ac reader activity
           |   |__histone H3Q5ser reader activity
           |   |__histone H3R8me2 reader activity
           |__histone H4 reader activity 7 rec.
           |   |__histone H4K5ac reader activity 1 rec.
           |   |__histone H4K8ac reader activity
           |   |__histone H4K12ac reader activity
           |   |__histone H4K16ac reader activity 1 rec.
           |   |__histone H4K20me1 reader activity 3 rec.
           |   |__histone H4K20me2 reader activity 2 rec.
           |   |__histone H4K20me3 reader activity 2 rec.
           |__ubiquitin-modified histone reader activity
           |__unmodified histone reader activity
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Is a chromatin-protein adaptor activity
Part of
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Synonyms
  • "epigenetic reader" BROAD
    "histone reader" EXACT
Secondary IDs
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