FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term histone reader activity ID (Ontology) GO:0140566 (Gene Ontology)
Definition A chromatin adaptor activity that brings together a protein and a specific form of histone, either modified by a post-translational modification, or the unmodified form. Histone readers have roles in many processes, including in centromere function or in modulating the accessibility of cis-regulatory regions to the transcription machinery.[ PubMed:11498575 PubMed:25688442 PubMed:31082667 PubMed:34726351 ]
Also Known As"histone reader"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Full annotation statements 
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 Genes
 histone reader activity (all annotations which use CV term, excluding "NOT" statements)
     enables | histone reader activity
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Vocabulary search 
  protein-macromolecule adaptor activity
   |__chromatin-protein adaptor activity
       |__histone reader activity  30 rec.
           |__histone H1 reader activity
           |   |__histone H1K26me1 reader activity
           |   |__histone H1K26me2 reader activity
           |__histone H2A reader activity
           |   |__histone H2AK5ac reader activity
           |   |__histone H2AK15ac reader activity
           |   |__histone H2AK15ub reader activity
           |   |__histone H2AS139pho reader activity
           |   |__histone H2AT120pho reader activity
           |__histone H2B reader activity
           |__histone H3 reader activity 16 rec.
           |   |__histone H3K4me1 reader activity 2 rec.
           |   |__histone H3K4me3 reader activity 8 rec.
           |   |__histone H3K9ac reader activity
           |   |__histone H3K9cr reader activity
           |   |__histone H3K9me2/3 reader activity 4 rec.
           |   |__histone H3K14ac reader activity 1 rec.
           |   |__histone H3K14ub reader activity
           |   |__histone H3K18ac reader activity
           |   |__histone H3K18cr reader activity
           |   |__histone H3K18ub reader activity
           |   |__histone H3K23ac reader activity
           |   |__histone H3K23ub reader activity
           |   |__histone H3K27ac reader activity
           |   |__histone H3K27cr reader activity
           |   |__histone H3K27me3 reader activity
           |   |__histone H3K36me3 reader activity 5 rec.
           |   |__histone H3K56ac reader activity
           |   |__histone H3Q5ser reader activity
           |   |__histone H3R8me2 reader activity
           |__histone H4 reader activity 6 rec.
           |   |__histone H4K5ac reader activity 1 rec.
           |   |__histone H4K8ac reader activity
           |   |__histone H4K12ac reader activity
           |   |__histone H4K16ac reader activity 1 rec.
           |   |__histone H4K20me1 reader activity 3 rec.
           |   |__histone H4K20me2 reader activity 2 rec.
           |   |__histone H4K20me3 reader activity 1 rec.
           |__ubiquitin-modified histone reader activity
           |__unmodified histone reader activity
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Is a chromatin-protein adaptor activity
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Synonyms
  • "epigenetic reader" BROAD
    "histone reader" EXACT
Secondary IDs
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