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| Term | iodotyrosine deiodinase activity | ID (Ontology) | GO:0140616 (Gene Ontology) |
| Definition | Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.[ PubMed:15289438 PubMed:18434651 PubMed:25395621 PubMed:27643701 ] | ||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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oxidoreductase activity |__oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond |__iodotyrosine deiodinase activity 1 rec. |
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Relationships
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| Is a | oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond | ||
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Synonyms & Secondary IDs
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External Crossreferences & Linkouts
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EC:1.21.1.1 Reactome:R-HSA-209921 "Monoiodinated tyrosine can be deiodinated" Reactome:R-HSA-209960 "Diiodinated tyrosine can be deiodinated" RHEA:32479 |
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