FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term histone H3K36me2/H3K36me3 demethylase activity ID (Ontology) GO:0140681 (Gene Ontology)
Definition Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.[ PubMed:21914792 ]
Also Known As "histone H3-tri/dimethyl-lysine-36 demethylase activity"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       2
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 histone H3K36me2/H3K36me3 demethylase activity (all annotations which use CV term, excluding "NOT" statements)       2
     enables | histone H3K36me2/H3K36me3 demethylase activity       2
Spanning Tree (Parents/Children)
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2-oxoglutarate-dependent dioxygenase activity__
histone H3 demethylase activity________________|
                                               histone H3K36 demethylase activity
                                                |__histone H3K36me2/H3K36me3 demethylase activity  2 rec.
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Is a histone H3K36 demethylase activity
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Synonyms
  • "histone H3-tri/dimethyl-lysine-36 demethylase activity" EXACT
    "histone H3K36me2 demethylase activity" BROAD
    "histone H3K36me3 demethylase activity" RELATED
Secondary IDs
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EC:1.14.11.69
MetaCyc:RXN-20643
RHEA:60236