FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term FAD-dependent H3K4me/H3K4me3 demethylase activity ID (Ontology) GO:0140682 (Gene Ontology)
Definition Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 4 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.[ PubMed:22473470 ]
Also Known As "histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity"
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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Relevant FlyBase reports
 Genes
 FAD-dependent H3K4me/H3K4me3 demethylase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | FAD-dependent H3K4me/H3K4me3 demethylase activity       1
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oxidoreductase activity
 |__oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen__
histone H3 demethylase activity                                                                            |
 |__histone H3K4 demethylase activity______________________________________________________________________|
                                                                                         FAD-dependent H3K4me/H3K4me3 demethylase activity  1 rec.
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Is a oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
histone H3K4 demethylase activity
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Synonyms
  • "histone H3-di/monomethyl-lysine-4 FAD-dependent demethylase activity" EXACT
    "histone H3K4me demethylase activity" RELATED
    "histone H3K4me2 demethylase activity" BROAD
Secondary IDs
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EC:1.14.99.66
RHEA:60244