FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity ID (Ontology) GO:0140933 (Gene Ontology)
Definition Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.[ PubMed:18820299 PubMed:29483298 ]
Also Known As"m(7)GpppN-mRNA hydrolase activity"
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Data ClassFieldDirect annotations
Genes (FBgn)GO_MOLECULAR_FUNCTION
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 Genes
 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
 NOT | enables | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
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  hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
   |__pyrophosphatase activity
       |__5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity  1 rec.
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Is a pyrophosphatase activity
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Synonyms
  • "m(7)GpppN-mRNA hydrolase activity" EXACT
Secondary IDs
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EC:3.6.1.62
RHEA:37371
RHEA:60868
RHEA:60872
RHEA:67484