FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
Help Close All Open All
General Information
Term histone H3K27 dimethyltransferase activity ID (Ontology) GO:0140952 (Gene Ontology)
Definition Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.
Also Known As "histone H3-K27 dimethylase activity" ; "histone H3K27 dimethylase activity" ; "histone H3K27 mono/dimethylase activity" (for all, see Synonyms field below)
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 histone H3K27 dimethyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | histone H3K27 dimethyltransferase activity       1
Spanning Tree (Parents/Children)
Only view relationship:
protein-lysine N-methyltransferase activity__
histone H3 methyltransferase activity________|
                                             histone H3K27 methyltransferase activity
                                              |__histone H3K27 dimethyltransferase activity  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a histone H3K27 methyltransferase activity
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "histone H3-K27 dimethylase activity" EXACT
    "histone H3-K27 dimethylation" BROAD
    "histone H3K27 dimethylase activity" EXACT
    "histone H3K27 dimethylation" BROAD
    "histone H3K27 mono/dimethylase activity" EXACT
    "histone lysine N-dimethyltransferase activity (H3-K27 specific)" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
EC:2.1.1.371
RHEA:64452