FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term histone H3K27 monomethyltransferase activity ID (Ontology) GO:0140953 (Gene Ontology)
Definition Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.
Also Known As "histone H3-K27 monomethylase activity" ; "histone H3K27 monomethylase activity" ; "histone lysine N-monomethyltransferase activity (H3-K27 specific)"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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Relevant FlyBase reports
 Genes
 histone H3K27 monomethyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | histone H3K27 monomethyltransferase activity       1
Spanning Tree (Parents/Children)
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protein-lysine N-methyltransferase activity__
histone H3 methyltransferase activity________|
                                             histone H3K27 methyltransferase activity
                                              |__histone H3K27 monomethyltransferase activity  1 rec.
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Is a histone H3K27 methyltransferase activity
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Synonyms
  • "histone H3-K27 methylation" BROAD
    "histone H3-K27 monomethylase activity" EXACT
    "histone H3K27 methylation" BROAD
    "histone H3K27 monomethylase activity" EXACT
    "histone lysine N-monomethyltransferase activity (H3-K27 specific)" EXACT
Secondary IDs
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EC:2.1.1.369
RHEA:60296