FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term histone H4K12 methyltransferase activity ID (Ontology) GO:0140984 (Gene Ontology)
Definition Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.[ PubMed:12086618 ]
Also Known As"histone H4 lysine 12-specific methyltransferase activity" ; "histone H4K12 methylation" ; "histone lysine N-methyltransferase activity (H4-K12 specific)" (for all, see Synonyms field below)
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Genes (FBgn)GO_MOLECULAR_FUNCTION
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 histone H4K12 methyltransferase activity (all annotations which use CV term, excluding "NOT" statements)
     enables | histone H4K12 methyltransferase activity
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protein methyltransferase activity
 |__protein-lysine N-methyltransferase activity__
lysine N-methyltransferase activity              |
 |__protein-lysine N-methyltransferase activity__|
histone methyltransferase activity               |
 |__histone H4 methyltransferase activity________|
                                                 histone H4K12 methyltransferase activity  1 rec.
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Is a protein-lysine N-methyltransferase activity
histone H4 methyltransferase activity
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Synonyms
  • "histone H4 lysine 12-specific methyltransferase activity" EXACT
    "histone H4K12 methylase activity" BROAD
    "histone H4K12 methylation" EXACT
    "histone lysine N-methyltransferase activity (H4-K12 specific)" EXACT
    "histone methylase activity (H4-K12 specific)" EXACT
    "histone methyltransferase activity (H4-K12 specific)" EXACT
    "histone-H4K12 methyltransferase activity" EXACT
Secondary IDs
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