FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term tRNA (guanine(26)-N2)-dimethyltransferase activity ID (Ontology) GO:0160104 (Gene Ontology)
Definition Catalysis of the reaction:guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = 2 H+ + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine.[ EC:2 ]
Also Known As "tRNA (guanine(26)-N(2))-dimethyltransferase activity" ; "tRNA (guanosine(26)-N(2))-dimethyltransferase activity" ; "tRNA (m(2)2G26)dimethyltransferase"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 tRNA (guanine(26)-N2)-dimethyltransferase activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | tRNA (guanine(26)-N2)-dimethyltransferase activity       1
Spanning Tree (Parents/Children)
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methyltransferase activity
 |__N-methyltransferase activity___________________________
tRNA methyltransferase activity                            |
 |__tRNA (guanine) methyltransferase activity______________|
S-adenosylmethionine-dependent methyltransferase activity  |
 |__tRNA (guanine) methyltransferase activity______________|
                                                           tRNA (guanine(26)-N2)-dimethyltransferase activity  1 rec.
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Is a N-methyltransferase activity
tRNA (guanine) methyltransferase activity
Part of
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Synonyms
  • "tRNA (guanine(26)-N(2))-dimethyltransferase activity" EXACT
    "tRNA (guanosine(26)-N(2))-dimethyltransferase activity" EXACT
    "tRNA (m(2)2G26)dimethyltransferase" EXACT
Secondary IDs
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EC:2.1.1.216
Reactome:R-HSA-6782416 "TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr)"
RHEA:43140