FB2026_03 , released September 17, 2026
CV Term Report
Help Close All Open All
General Information
Term negative regulation of pyruvate decarboxylation to acetyl-CoA ID (Ontology) GO:0160218 (Gene Ontology)
Definition Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions.[ PubMed:26942675 PubMed:36849569 PubMed:37754565 ]
Also Known As"negative regulation of acetyl-CoA biosynthetic process from pyruvate"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

    • Results list data from multiple species. Choose a record type above to open its HitList.
Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Genes (FBgn)GO_BIOLOGICAL_PROCESS
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 negative regulation of pyruvate decarboxylation to acetyl-CoA (all annotations which use CV term, excluding "NOT" statements)
     involved_in | negative regulation of pyruvate decarboxylation to acetyl-CoA
Spanning Tree (Parents/Children)
Only view relationship:
Vocabulary search 
pyruvate decarboxylation to acetyl-CoA
 |__regulation of pyruvate decarboxylation to acetyl-CoA_________________
negative regulation of biosynthetic process                              |
 |__negative regulation of acetyl-CoA biosynthesis_______________________|
negative regulation of phosphorus metabolic process                      |
 |__negative regulation of acetyl-CoA biosynthesis_______________________|
negative regulation of nucleobase-containing compound metabolic process  |
 |__negative regulation of acetyl-CoA biosynthesis_______________________|
regulation of acyl-CoA biosynthetic process                              |
 |__regulation of pyruvate decarboxylation to acetyl-CoA_________________|
 |__negative regulation of acetyl-CoA biosynthesis_______________________|
negative regulation of small molecule metabolic process                  |
 |__negative regulation of acetyl-CoA biosynthesis_______________________|
                                                                         negative regulation of pyruvate decarboxylation to acetyl-CoA  1 rec.
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a regulation of pyruvate decarboxylation to acetyl-CoA
negative regulation of acetyl-CoA biosynthesis
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "negative regulation of acetyl-CoA biosynthetic process from pyruvate" EXACT
Secondary IDs
hide External Crossreferences & Linkouts