FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

transcription pausing by RNA polymerase II

ID (Ontology)

GO:0160239 (Gene Ontology)

Definition

A transcription halt following transcription initiation but prior to elongation, during which RNA polymerase II pauses approximately 20-60 nucleotides downstream of the transcriptional start site before proceeding into productive elongation. Transcription pausing starts following phosphorylation of the C-terminal domain (CTD) of RNA polymerase II subunit POLR2A at Ser-5 and stops following phosphorylation of POLR2A by the P-TEFb complex.[ PubMed:33271312 PubMed:35816930 ]

Also Known As

"promoter proximal pausing by RNA polymerase II"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
transcription pausing by RNA polymerase II (all annotations which use CV term, excluding "NOT" statements)
involved_in \| transcription pausing by RNA polymerase II

Spanning Tree (Parents/Children)

DNA-templated transcription
 |__transcription by RNA polymerase II__
RNA metabolic process                   |
 |__RNA biosynthetic process____________|
nucleic acid biosynthetic process       |
 |__RNA biosynthetic process____________|
                                        transcription pausing by RNA polymerase II  2 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	RNA biosynthetic process
Part of	transcription by RNA polymerase II
Synonyms & Secondary IDs
Synonyms
	"promoter proximal pausing by RNA polymerase II" EXACT
Secondary IDs

External Crossreferences & Linkouts