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General Information
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| Term |
transcription pausing by RNA polymerase II |
ID (Ontology) |
GO:0160239 (Gene Ontology) |
| Definition |
A transcription halt following transcription initiation but prior to elongation, during which RNA polymerase II pauses approximately 20-60 nucleotides downstream of the transcriptional start site before proceeding into productive elongation. Transcription pausing starts following phosphorylation of the C-terminal domain (CTD) of RNA polymerase II subunit POLR2A at Ser-5 and stops following phosphorylation of POLR2A by the P-TEFb complex.[ PubMed:33271312 PubMed:35816930 ] |
| Also Known As |
"promoter proximal pausing by RNA polymerase II" |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_BIOLOGICAL_PROCESS | 2 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Genes |
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transcription pausing by RNA polymerase II (all annotations which use CV term, excluding "NOT" statements) | 2 | involved_in | transcription pausing by RNA polymerase II | 2 |
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