FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

cholesterol 7-desaturase [NAD(P)H] activity

ID (Ontology)

GO:0170056 (Gene Ontology)

Definition

Catalysis of the reaction: cholesterol + H+ + NAD(P)H + O2 = 7-dehydrocholesterol + 2 H2O + NAD(P)+.[ EC:1 PubMed:21632547 PubMed:31521708 ]

Also Known As

"C-7 cholesterol dehydrogenase" ; "cholesterol 7,8-dehydrogenase"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
cholesterol 7-desaturase [NAD(P)H] activity (all annotations which use CV term, excluding "NOT" statements)
enables \| cholesterol 7-desaturase [NAD(P)H] activity

Spanning Tree (Parents/Children)

  oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
   |__sterol desaturase activity
       |__cholesterol 7-desaturase [NAD(P)H] activity  1 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	sterol desaturase activity
Part of
Synonyms & Secondary IDs
Synonyms
	"C-7 cholesterol dehydrogenase" EXACT "cholesterol 7,8-dehydrogenase" EXACT
Secondary IDs

External Crossreferences & Linkouts
	EC:1.14.19.21 MetaCyc:RXN-16379 RHEA:45024 RHEA:51644