FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
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General Information
Term cholesterol 7-desaturase [NAD(P)H] activity ID (Ontology) GO:0170056 (Gene Ontology)
Definition Catalysis of the reaction: cholesterol + H+ + NAD(P)H + O2 = 7-dehydrocholesterol + 2 H2O + NAD(P)+.[ EC:1 PubMed:21632547 PubMed:31521708 ]
Also Known As "C-7 cholesterol dehydrogenase" ; "cholesterol 7,8-dehydrogenase"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
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Relevant FlyBase reports
 Genes
 cholesterol 7-desaturase [NAD(P)H] activity (all annotations which use CV term, excluding "NOT" statements)       1
     enables | cholesterol 7-desaturase [NAD(P)H] activity       1
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  oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
   |__sterol desaturase activity
       |__cholesterol 7-desaturase [NAD(P)H] activity  1 rec.
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Is a sterol desaturase activity
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Synonyms
  • "C-7 cholesterol dehydrogenase" EXACT
    "cholesterol 7,8-dehydrogenase" EXACT
Secondary IDs
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EC:1.14.19.21
MetaCyc:RXN-16379
RHEA:45024
RHEA:51644