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| Term | RQC-trigger complex | ID (Ontology) | GO:0180022 (Gene Ontology) | |||||||
| Definition | A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B.[ PubMed:12077347 PubMed:28757607 PubMed:32099016 ] | |||||||||
| Also Known As | "activating signal cointegrator 1 complex" ; "ASC-1 complex" ; "RQT complex" | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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cellular_component |__protein-containing complex |__RQC-trigger complex 1 rec. |
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| Is a | protein-containing complex | ||
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