FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

regulation of extrinsic apoptotic signaling pathway via death domain receptors

ID (Ontology)

GO:1902041 (Gene Ontology)

Definition

Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.[ PubMed:17245429 ]

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
regulation of extrinsic apoptotic signaling pathway via death domain receptors (all annotations which use CV term, excluding "NOT" statements)
involved_in \| regulation of extrinsic apoptotic signaling pathway via death domain receptors

Spanning Tree (Parents/Children)

extrinsic apoptotic signaling pathway
 |__extrinsic apoptotic signaling pathway via death domain receptors__
 |__regulation of extrinsic apoptotic signaling pathway_______________|
regulation of apoptotic signaling pathway                             |
 |__regulation of extrinsic apoptotic signaling pathway_______________|
                                                                      regulation of extrinsic apoptotic signaling pathway via death domain receptors  3 rec.
                                                                       |__negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 2 rec.
                                                                       |   |__negative regulation of TRAIL-activated apoptotic signaling pathway
                                                                       |__positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
                                                                       |   |__positive regulation of TRAIL-activated apoptotic signaling pathway
                                                                       |__regulation of TRAIL-activated apoptotic signaling pathway
                                                                           |__negative regulation of TRAIL-activated apoptotic signaling pathway
                                                                           |__positive regulation of TRAIL-activated apoptotic signaling pathway

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	regulation of extrinsic apoptotic signaling pathway
Part of
Synonyms & Secondary IDs
Synonyms
	"regulation of death receptor-mediated apoptosis" NARROW
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-3371378 "Regulation by c-FLIP"