FB2026_03 , released September 17, 2026
CV Term Report
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Term methylcrotonoyl-CoA carboxylase complex ID (Ontology) GO:1905202 (Gene Ontology)
Definition A protein complex capable of methylcrotonoyl-CoA carboxylase activity. In mammals, it is a mitochondrial complex comprising a dodecamer of 6 alpha and 6 beta subunits: MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation; MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.[ PubMed:15868465 PubMed:17360195 PubMed:22158123 PubMed:22869039 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 methylcrotonoyl-CoA carboxylase complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | methylcrotonoyl-CoA carboxylase complex       --
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  protein-containing complex
   |__catalytic complex
       |__methylcrotonoyl-CoA carboxylase complex  3 rec.
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