FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

GATOR1 complex

ID (Ontology)

GO:1990130 (Gene Ontology)

Definition

A GTPase-activating protein (GAP) complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, the GATOR1 complex consists of DEPDC5, NPRL2, and NPRL3. In S. cerevisiae, this complex is referred to as SEACIT and contains the Iml1p, Npr2p, and Npr3p proteins.[ PubMed:21900499 PubMed:23723238 PubMed:23974112 PubMed:25934700 PubMed:28199306 PubMed:29199950 ]

Also Known As

"IML1 complex" ; "SEACIT complex"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_CELLULAR_COMPONENT

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
GATOR1 complex (all annotations which use CV term, excluding "NOT" statements)
part_of \| GATOR1 complex	--

Spanning Tree (Parents/Children)

cellular_component
 |__protein-containing complex__
protein-containing complex      |
 |__Seh1-associated complex_____|
                                GATOR1 complex  4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein-containing complex
Part of	Seh1-associated complex
Synonyms & Secondary IDs
Synonyms
	"IML1 complex" EXACT "SEACIT complex" EXACT
Secondary IDs

External Crossreferences & Linkouts