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| Term | uniplex complex | ID (Ontology) | GO:1990246 (Gene Ontology) | ||||||||||||||
| Definition | A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.[ PubMed:24231807 ] | ||||||||||||||||
| Also Known As | "mitochondrial uniporter complex" ; "mitochondrial uniporter holocomplex" | ||||||||||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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mitochondrial inner membrane |__inner mitochondrial membrane protein complex__ cation channel complex | |__calcium channel complex_______________________| membrane protein complex | |__inner mitochondrial membrane protein complex__| mitochondrial protein-containing complex | |__inner mitochondrial membrane protein complex__| uniplex complex 8 rec. |
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calcium channel complex inner mitochondrial membrane protein complex |
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