FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term Atg1/ULK1 kinase complex ID (Ontology) GO:1990316 (Gene Ontology)
Definition A protein complex consisting of Atg1 (or Atg1 homologs e.g. ULK1, ULK2 in mammals) and Atg13 along with other proteins that regulate its function (e.g. Atg17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.[ PubMed:15743910 PubMed:19211835 PubMed:19258318 PubMed:19597335 PubMed:22885598 ]
Also Known As"ATG1 kinase complex" ; "ATG1-ATG13 complex" ; "ATG1/ULK1 signaling complex" (for all, see Synonyms field below)
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 Atg1/ULK1 kinase complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | Atg1/ULK1 kinase complex       --
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intracellular anatomical structure
 |__cytoplasm________________________________
cellular anatomical structure                |
 |__cytoplasm________________________________|
protein kinase complex                       |
 |__serine/threonine protein kinase complex__|
                                             Atg1/ULK1 kinase complex  5 rec.
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Is a serine/threonine protein kinase complex
Part of cytoplasm
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Synonyms
  • "ATG1 kinase complex" EXACT
    "ATG1-ATG13 complex" EXACT
    "ATG1/ULK1 signaling complex" EXACT
    "Atg1p signalling complex" EXACT
    "autophagy-initiation complex" EXACT[ PubMed:26754330 ]
    "ULK complex" EXACT[ PubMed:28816597 ]
    "ULK1 complex" EXACT[ PubMed:26921696 ]
    "ULK1 signaling complex" EXACT
    "ULK1-ATG13-FIP200 complex" EXACT
    "ULK1-ATG13-RB1CC1 complex" EXACT
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