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| Term | CLOCK-BMAL transcription complex | ID (Ontology) | GO:1990513 (Gene Ontology) | |||||||
| Definition | Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.[ PubMed:23229515 ] | |||||||||
| Also Known As | "CLOCK/BMAL complex" | |||||||||
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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transcription regulator complex_____ nuclear protein-containing complex__| RNA polymerase II transcription regulator complex |__CLOCK-BMAL transcription complex 1 rec. |
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| Is a | RNA polymerase II transcription regulator complex | ||
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