FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term Lsm1-7-Pat1 complex ID (Ontology) GO:1990726 (Gene Ontology)
Definition A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway.[ PubMed:19121818 PubMed:23620288 PubMed:24139796 PubMed:27627834 PubMed:28768202 ]
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 Lsm1-7-Pat1 complex (all annotations which use CV term, excluding "NOT" statements)
     part_of | Lsm1-7-Pat1 complex
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  protein-containing complex
   |__Sm-like protein family complex
       |__Lsm1-7-Pat1 complex  5 rec.
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