FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term FNIP-folliculin RagC/D GAP ID (Ontology) GO:1990877 (Gene Ontology)
Definition A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.[ PubMed:24095279 PubMed:26387955 PubMed:34805795 ]
Also Known As "BFC complex" ; "FLCN-FNIP1 complex" ; "FLCN-FNIP2 complex" (for all, see Synonyms field below)
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Genes (FBgn)GO_CELLULAR_COMPONENT
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 FNIP-folliculin RagC/D GAP (all annotations which use CV term, excluding "NOT" statements)
     part_of | FNIP-folliculin RagC/D GAP
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  enzyme activator complex
   |__GTPase activator complex
       |__FNIP-folliculin RagC/D GAP  1 rec.
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Is a GTPase activator complex
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Synonyms
  • "BFC complex" EXACT[ PubMed:34805795 ]
    "FLCN-FNIP1 complex" EXACT
    "FLCN-FNIP2 complex" EXACT
    "FNIP-Folliculin RagC/D GAP complex" EXACT
    "Lst4-Lst7 complex" EXACT
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