FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

TOM-TIM23-SORT-mediated protein insertion into the mitochondrial inner membrane

ID (Ontology)

GO:7770060 (Gene Ontology)

Definition

The import of proteins from the cytosol across the outer mitochondrial membrane and laterally inserted into the inner membrane. Typically acting on single-pass transmembrane proteins with an N-terminal targeting sequence and an internal hydrophobic stop-transfer sequence which targets them for lateral insertion.[ PubMed:36931257 ]

Also Known As

"TOM-TIM23-SORT pathway"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
TOM-TIM23-SORT-mediated protein insertion into the mitochondrial inner membrane (all annotations which use CV term, excluding "NOT" statements)
involved_in \| TOM-TIM23-SORT-mediated protein insertion into the mitochondrial inner membrane

Spanning Tree (Parents/Children)

inner mitochondrial membrane organization__
mitochondrial protein import pathway_______|
                                           protein insertion into mitochondrial inner membrane
                                            |__TOM-TIM23-SORT-mediated protein insertion into the mitochondrial inner membrane  13 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein insertion into mitochondrial inner membrane
Part of
Synonyms & Secondary IDs
Synonyms
	"stop-transfer pathway" RELATED "TOM-TIM23-SORT pathway" EXACT
Secondary IDs

External Crossreferences & Linkouts