FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

insulator

ID (Ontology)

SO:0000627 (Sequence Ontology)

Definition

A regulatory region that 1) when located between a CRM and a gene's promoter prevents the CRM from modulating that genes expression and 2) acts as a chromatin boundary element or barrier that can block the encroachment of condensed chromatin from an adjacent region.[ PubMed:12154228 ]

Also Known As

"INSDC_qualifier:insulator" ; "insulator element"

Comment

Links to External Ontologies

SO.org

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	FEATURE_TYPE
Genes (FBgn)	SO_TERMS
Sequence Features (FBsf)	FEATURE_TYPE

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes	Sequence Features
insulator (all annotations which use CV term, excluding "NOT" statements)

Spanning Tree (Parents/Children)

  transcriptional_cis_regulatory_region
   |__cis_regulatory_module
       |__insulator  7692 rec.
           |__boundary_element
           |__enhancer_blocking_element
           |__insulator_binding_site

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	cis_regulatory_module
Part of
Synonyms & Secondary IDs
Synonyms
	"INSDC_feature:regulatory" BROAD "INSDC_qualifier:insulator" EXACT "insulator element" EXACT
Secondary IDs

External Crossreferences & Linkouts
	http://en.wikipedia.org/wiki/Insulator_(genetics) "wiki"