Aberration Dmel\Df(3L)BSC448

General Information
Symbol	Dmel\Df(3L)BSC448	Species	D. melanogaster
Name		FlyBase ID	FBab0045272
Feature type	chromosomal_deletion

Computed Breakpoints include	[77C6-77C6];[77E4-77E4];
Deleted segment	77C6--77E4
Map ( GBrowse )	Untitled Document
Sequence coordinates	3L:20,500,567..20,500,986 (Df(3L)BSC448:bk1) (Bloomington Drosophila Stock Center, 2008.8.7) 3L:20,723,658..20,723,658 (Df(3L)BSC448:bk2) (Bloomington Drosophila Stock Center, 2008.8.7)
Member of large scale dataset(s)	Dfs_BSC_set2 A set of ~800 largely isogenic deficiency stocks created by FLP-induced recombination between FRT-carrying transgenic insertions; molecularly defined deletion endpoints correspond to initial location of the progenitor insertions. Designed to fill gaps in deletion coverage and breakpoint placement; also used to replace older available deficiencies that have not been molecularly mapped. (Cook et al., 2012)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Aberration
Cytological Order
Progenitor	P{XP}d06749 (Christensen et al., 2008.4.15) PBac{WH}CG32425^f01627 (Christensen et al., 2008.4.15)
Mutagen	FLPase (Christensen et al., 2008.4.15)
Class of aberration (relative to progenitor)	chromosomal_deletion (Christensen et al., 2008.4.15)
Breakpoints	77C6;77E4 (FlyBase Curators, 2008)
Causes alleles
Carries alleles
Transposon Insertions	P+PBac{XP5.WH5}BSC448 (Christensen et al., 2008.4.15)
Formalized genetic data
Genetic mapping information
Comments
Comments on Cytology
	The cytological breakpoints of Df(3L)BSC448 predicted from the Release 5 genomic coordinates of the progenitor PBac{WH}CG32425^f01627 and P{XP}d06749 insertion sites are 77C6;77E4. (Christensen et al., 2008.4.15)
Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	kni (Christensen et al., 2008.4.15)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations	Inferred to overlap with: Df(3L)BSC796. (Christensen et al., 2009.5.6)
NOT in combination with other aberrations
Stocks ( 1 )
Bloomington	24952 w¹¹¹⁸; Df(3L)BSC448/TM6C, Sb¹ cu¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The presence of P+PBac{XP5.WH5}BSC448 was verified using the PCR methods and primers described in FBrf0175003. (Christensen et al., 2008.4.15)
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Df(3L)BSC448 (FlyBase, 2007, Christensen et al., 2008.4.15, FlyBase Curators, 2008, Christensen et al., 2009.5.6, Cook et al., 2012)
Name Synonym
Secondary FlyBase IDs

References ( 8 )
Research paper	Cook et al., 2012, Genome Biol. 13(3): R21 The generation of chromosomal deletions to provide extensive coverage and subdivision of the Drosophila melanogaster genome. [FBrf0219066]
Supplementary material	Cook et al., 2012, Genome Biol. 13(3): Additional file 1. Breakpoints and characterization of BSC deletions. [FBrf0219069]
Personal communication to FlyBase	Christensen et al., 2009.5.6, Isolation and characterization of Df(3L)BSC796. Isolation and characterization of Df(3L)BSC796. [FBrf0207904] Bloomington Drosophila Stock Center, 2008.8.7, Release 5 sequence coordinates of BSC deficiencies. Release 5 sequence coordinates of BSC deficiencies. [FBrf0205560] Christensen et al., 2008.4.15, Isolation and characterization of Df(3L)BSC448. Isolation and characterization of Df(3L)BSC448. [FBrf0204483]
FlyBase analysis	Millburn et al., 2012.8.1, Lines in aberration datasets (files on ftp site). Lines in aberration datasets (files on ftp site). [FBrf0219195] FlyBase Curators, 2008, Release 5 estimated cytology of aberrations with sequence-defined breakpoints. Release 5 estimated cytology of aberrations with sequence-defined breakpoints. [FBrf0206255] FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]