FB2025_01 , released February 20, 2025
Allele: Dmel\Rpt4G0345
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General Information
Symbol
Dmel\Rpt4G0345
Species
D. melanogaster
Name
FlyBase ID
FBal0098106
Feature type
allele
Associated gene
Dmel\Rpt4
Associated Insertion(s)
P{lacW}Rpt4G0345
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Schäfer et al., 1999.6.15)
Progenitor genotype
Associated Insertion(s)
P{lacW}Rpt4G0345
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
AJ426716
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous adults are smaller in size and weigh less than wild-type controls.

      (Gaur et al., 2013)

      Lethality occurs during the first and second larval instars.

      (Peter et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Rpt4[+]/Rpt4G0345 is a suppressor of partially lethal - majority die phenotype of Ras85DV12.UAS, Scer\GAL4ey.PU

      (Gaur et al., 2013)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Rpt4G0345/+ partially suppresses the semi-lethality caused by expression of Ras85DV12.Scer\UAS under the control of Scer\GAL4ey.PU at 21-22[o]C.

      (Gaur et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      P{lacW} not verified as causing the lethality.

      (Schäfer et al., 1999.6.15)
      External Crossreferences and Linkouts ( 1 )
      Crossreferences
      GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Rpt4G0345
      (Gaur et al., 2013)
      l(1)G0345
      (Peter et al., 2002)
      l(1)G0345G0345
      Name Synonyms
      Secondary FlyBase IDs
        References (3)