FlyBase Allele Report: Dmel\pins[UAS.cYa]

General Information

Symbol

Dmel\pins^UAS.cYa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Yu

FlyBase ID

FBal0104443

Feature type

allele

Associated gene

Dmel\pins

Associated Insertion(s)

Carried in Construct

P{UAS-pins.Y}

Also Known As

uas-pins

Key Links

Transgenic product class

wild_type

(Yu et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Yu et al., 2000)

Mutagen

in vitro construct

(Yu et al., 2000)

Progenitor genotype

Carried in construct

P{UAS-pins.Y}

Cytology

Description

UASt regulatory sequences drive expression of full length pins.

(Yu et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

pins

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

pins^UAS.cYa/Scer\GAL4^erm.PU is a suppressor | partially of abnormal neuroanatomy | third instar larval stage phenotype of Pfdn2^Δ10, pins^P89

(Zhang et al., 2016)

pins^UAS.cYa/Scer\GAL4^erm.PU is a suppressor | partially of increased cell number | third instar larval stage phenotype of Pfdn2^Δ10, pins^P89

(Zhang et al., 2016)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^wor.PA/pins^UAS.cYa rescues pins^P62

(Smith and Prehoda, 2011)

pins^UAS.cYa/Scer\GAL4^sca-P309 rescues pins^P62

(Yu et al., 2000)

pins^UAS.cYa/Scer\GAL4^sca-P309 rescues pins^P89

(Yu et al., 2000)

Partially rescues

pins^UAS.cYa/Scer\GAL4^erm.PU partially rescues pins^P89

(Zhang et al., 2016)

Comments

The dramatically increased total average number of brain neuroblast in third instar larvae characteristic for Pfdn2^Δ10;pins^P89 double mutants can be partially rescued by expression of pins^Scer\UAS.cYa under the control of Scer\GAL4^erm.PU in the double mutant background.

(Zhang et al., 2016)

Expression of raps^Scer\UAS.cYa via the neuroblast-specific Scer\GAL4^wor.PA driver rescues the mitotic spindle orientation defect in raps^P62 mutants cells.

(Smith and Prehoda, 2011)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

pins^Scer\UAS.cYa

(Yu et al., 2000)

pins^UAS.cYa

raps^Scer\UAS.cYa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Yu

(Yu et al., 2000)

Secondary FlyBase IDs

References (3)

Report Sections

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