FlyBase Allele Report: Dmel\Lsd-2[UAS.EGFP]

General Information

Symbol

Dmel\Lsd-2^UAS.EGFP

Species

D. melanogaster

Name

FlyBase ID

FBal0147805

Feature type

allele

Associated gene

Dmel\Lsd-2

Associated Insertion(s)

Carried in Construct

P{UAS-Lsd-2.EGFP}

Key Links

Transgenic product class

wild_type

(Gronke, 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Gronke, 2003)

Mutagen

in vitro construct

(Gronke, 2003, Gronke et al., 2003)

Progenitor genotype

Lsd-2^UAS.cGa

(Gronke, 2003)

Carried in construct

P{UAS-Lsd-2.EGFP}

Cytology

Description

EGFP has been fused to the C terminal end of Lsd-2.

(Gronke, 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Lsd-2

Tagged with

EGFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates Parkinson's disease 1

modeled by Hsap\SNCA^UAS.cFa

(Girard et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

lipid droplet | adult stage | increased number, with Scer\GAL4^ninaE.PT

(Girard et al., 2021)

photoreceptor neuron | adult stage, with Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, enhanceable by Hsap\SNCA^UAS.cFa/Scer\GAL4^GMR.PU

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | adult stage | increased number phenotype, enhanceable by Hsap\SNCA^UAS.cFa/Scer\GAL4^GMR.PU

(Girard et al., 2021)

NOT Enhanced by

Statement

Reference

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-enhanceable | somatic clone - tissue specific by Fatp1^k10307/Fatp1^k10307

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | adult stage | increased number phenotype, non-enhanceable | somatic clone - tissue specific by Fatp1^k10307/Fatp1^k10307

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-enhanceable by mdy^QX25/mdy^QX25

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | adult stage | increased number phenotype, non-enhanceable by mdy^QX25/mdy^QX25

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-enhanceable by bmm^JF01946, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | adult stage | increased number phenotype, non-enhanceable by bmm^JF01946, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

NOT suppressed by

Statement

Reference

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-suppressible | somatic clone - tissue specific by Fatp1^k10307/Fatp1^k10307

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | increased number | adult stage phenotype, non-suppressible | somatic clone - tissue specific by Fatp1^k10307/Fatp1^k10307

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-suppressible by mdy^QX25/mdy^QX25

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | increased number | adult stage phenotype, non-suppressible by mdy^QX25/mdy^QX25

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has photoreceptor neuron | adult stage phenotype, non-suppressible by bmm^JF01946, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Lsd-2^UAS.EGFP, Scer\GAL4^ninaE.PT has lipid droplet | increased number | adult stage phenotype, non-suppressible by bmm^JF01946, Scer\GAL4^ninaE.PT

(Girard et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Lsd-2^{Scer\UAS.T:Avic\GFP-EGFP}

Lsd-2^UAS.EGFP

Name Synonyms

Secondary FlyBase IDs

References (12)

Report Sections

Open Close