FlyBase Allele Report: Dmel\Tl[UAS.cHa]

General Information

Symbol

Dmel\Tl^UAS.cHa

Species

D. melanogaster

Name

FlyBase ID

FBal0181209

Feature type

allele

Associated gene

Dmel\Tl

Associated Insertion(s)

Carried in Construct

P{UAS-Tl.H}

Also Known As

UAS-Toll-1

Key Links

Transgenic product class

wild_type

(Hu et al., 2004)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Hu et al., 2004)

Mutagen

in vitro construct

(Hu et al., 2004)

Progenitor genotype

Carried in construct

P{UAS-Tl.H}

Cytology

Description

Encodes wild-type Tl.

(Hu et al., 2004)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^da.G32

(Yagi et al., 2010)

Phenotype Manifest In

adult abdomen, with Scer\GAL4^32B

(Yagi et al., 2010)

adult abdomen, with Scer\GAL4^71B

(Yagi et al., 2010)

anterior crossvein, with Scer\GAL4^dpp.PS

(Yagi et al., 2010)

anterior crossvein, with Scer\GAL4^e22c

(Yagi et al., 2010)

anterior crossvein, with Scer\GAL4^ptc-559.1

(Yagi et al., 2010)

eye, with Scer\GAL4^GMR.PF

(Yagi et al., 2010)

eye, with Scer\GAL4^lz-gal4

(Yagi et al., 2010)

posterior crossvein, with Scer\GAL4^e22c

(Yagi et al., 2010)

Detailed Description

Statement

Reference

Expression of Tl^Scer\UAS.cHa under the control of Scer\GAL4^AM29 has no affect on the targeting of DM6 olfactory neuron axons.

(Ward et al., 2015)

Expression of Tl^Scer\UAS.cHa under the control of either Scer\GAL4^32B or Scer\GAL4^71B results in an abdominal closure defect.

Expression of Tl^Scer\UAS.cHa under the control of Scer\GAL4^e22c results in both an anterior and posterior cross vein defect in the wing.

Expression of Tl^Scer\UAS.cHa under the control of either Scer\GAL4^dpp.PS or Scer\GAL4^ptc-559.1 results in an anterior cross vein defect in the wing.

Expression of Tl^Scer\UAS.cHa under the control of either Scer\GAL4^GMR.PF or Scer\GAL4^lz-gal4 generates a rough eye phenotype.

(Yagi et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Carried in a plasmid and transfected into S2 cells.

(Hu et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Tl^Scer\UAS.cHa

Tl^UAS.cHa

Toll (wt)

(Hu et al., 2004)

Toll-781C

(Hu et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close