Allele Dmel\t^Scer\UAS.cTa

General Information
Symbol	Dmel\t^Scer\UAS.cTa	Species	D. melanogaster
Name	Saccharomyces cerevisiae UAS construct a of True	FlyBase ID	FBal0195390
Feature type	allele	Associated gene	Dmel\t

Allele class
Mutagen	in vitro construct - regulatory fusion
Recent Updates
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen	in vitro construct - regulatory fusion (True et al., 2005)
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Scer\UAS regulatory sequences drive expression of the complete 2009 bp t cDNA (RH41996). (True et al., 2005)
Carried in construct	P{UAS-t.T} (Jeong et al., 2008, True et al., 2005, Wittkopp et al., 2009, de Navascués and Modolell, 2010)
Cytology
Phenotypic Data
Phenotypic Class
	body color defective, with Scer\GAL4^pnr-MD237 (True et al., 2005, Wittkopp et al., 2009)
Phenotype Manifest In
	adult cuticle, with Scer\GAL4^pnr-MD237 (Wittkopp et al., 2009) mesothoracic tergum, with Scer\GAL4^pnr-MD237 (True et al., 2005)
Detailed Description
	Statement Reference Expression of t[Scer\UAS.cTa] under the control of Scer\GAL4[pnr-MD237] causes increased brown pigmentation in the abdominal cuticle. (Wittkopp et al., 2009) Expression of t^Scer\UAS.cTa under the control of Scer\GAL4^pnr-MD237 causes the presence of a dark stripe of ectopic melanin along the dorsal midline, particularly on the notum. (True et al., 2005)
External Data
Linkouts
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Other
Statement Reference Scer\GAL4^pnr-MD237, t^Scer\UAS.cTa, y^Scer\UAS.cCa has body color defective phenotype (Jeong et al., 2008) Scer\GAL4^pnr-MD237, t^Scer\UAS.cTa, y^unspecified has body color defective phenotype (Jeong et al., 2008)
Phenotype Manifest In
Other
Statement Reference Scer\GAL4^pnr-MD237, t^Scer\UAS.cTa, y^Scer\UAS.cCa has adult cuticle phenotype (Jeong et al., 2008) Scer\GAL4^pnr-MD237, t^Scer\UAS.cTa, y^unspecified has adult cuticle phenotype (Jeong et al., 2008)
Additional Comments
Genetic Interactions
Statement Reference Simultaneous co-expression of e[Scer\UAS.cWa] and t[Scer\UAS.cTa] under the control of Scer\GAL4[pnr-MD237] results in a pigmentation phenotype in the abdominal cuticle that is intermediate to that caused by expression of either e[Scer\UAS.cWa] or t[Scer\UAS.cTa] alone. (Wittkopp et al., 2009) Expression of t^Scer\UAS.cTa under the control of Scer\GAL4^pnr-MD237 in a y^unspecified background produces ectopic brown pigment in the Scer\GAL4^pnr-MD237 expression domain of the adult abdomen in males. Co-expression of both y^Scer\UAS.cCa and t^Scer\UAS.cTa under the control of Scer\GAL4^pnr-MD237 produces dramatic black pigmentation in the Scer\GAL4^pnr-MD237 expression domain of the adult abdomen in males. (Jeong et al., 2008)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Rescues	Scer\GAL4^C-765/t^Scer\UAS.cTa rescues t¹ (True et al., 2005) Scer\GAL4^C-765/t^Scer\UAS.cTa rescues t⁵ (True et al., 2005) Scer\GAL4^ptc-559.1/t^Scer\UAS.cTa rescues t¹ (True et al., 2005) Scer\GAL4^ptc-559.1/t^Scer\UAS.cTa rescues t⁵ (True et al., 2005)
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	t^Scer\UAS.cTa
Name Synonym	Saccharomyces cerevisiae UAS construct a of True
Secondary FlyBase IDs

References ( 4 )
Research paper	de Navascués and Modolell, 2010, Mech. Dev. 127(9-12): 393--406 The pronotum LIM-HD gene tailup is both a positive and a negative regulator of the proneural genes achaete and scute of Drosophila. [FBrf0212072] Wittkopp et al., 2009, Science 326(5952): 540--544 Intraspecific polymorphism to interspecific divergence: genetics of pigmentation in Drosophila. [FBrf0209245] Jeong et al., 2008, Cell 132(5): 783--793 The evolution of gene regulation underlies a morphological difference between two Drosophila sister species. [FBrf0203102] True et al., 2005, PLoS Genet. 1(5): e63 Drosophila tan encodes a novel hydrolase required in pigmentation and vision. [FBrf0191392]

Allele Dmel\tScer\UAS.cTa

Allele Dmel\t^Scer\UAS.cTa