FB2025_01 , released February 20, 2025
Allele: Dmel\Eps-15ΔDPF.UAS
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General Information
Symbol
Dmel\Eps-15ΔDPF.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0219696
Feature type
allele
Associated gene
Dmel\Eps-15
Associated Insertion(s)
Carried in Construct
P{UAS-Eps-15.ΔDPF}
Key Links
Transgenic product class
inframe_deletion
(Koh et al., 2007)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Koh et al., 2007)
Mutagen
in vitro construct
(Koh et al., 2007)
Progenitor genotype
Carried in construct
P{UAS-Eps-15.ΔDPF}
Cytology
Description

UASt regulatory sequences drive expression of a truncated form of Eps-15 (amino acid residues 1-639).

(Koh et al., 2007)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Eps-15
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4elav-C155/Eps-15ΔDPF.UAS partially rescues Eps-15Δ29/Eps-15e75

      (Koh et al., 2007)

      Eps-15ΔDPF.UAS/Scer\GAL4elav.PLu partially rescues Eps-15Δ29/Eps-15e75

      (Koh et al., 2007)
      Comments

      Expression of Eps-15ΔDPF.Scer\UAS under the control of either Scer\GAL4elav-C155 or Scer\GAL4elav.PLu partially rescues the supernumerary bouton phenotype seen at Eps-15Δ29/Eps-15e75 larval neuromuscular junctions. The reduced dye uptake seen at the mutant neuromuscular junctions is also partially rescued.

      (Koh et al., 2007)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Eps-15ΔDPF.Scer\UAS
      Eps-15ΔDPF.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)