FB2025_01 , released February 20, 2025
Allele: Dmel\RalaG20V.cMa.UAS
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General Information
Symbol
Dmel\RalaG20V.cMa.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0221634
Feature type
allele
Associated gene
Dmel\Rala
Associated Insertion(s)
Carried in Construct
P{UAS-Ral.G20V.M}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Mirey et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-Ral.G20V.M}
Cytology
Description

UAS regulatory sequences drive expression of a constitutively active form of Rala.

(Mirey et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Rala
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of RalaG20V.cMa.Scer\UAS under the control of Scer\GAL4GMR.PF results in a weak rough eye phenotype.

      Flies expressing RalaG20V.cMa.Scer\UAS under the control of Scer\GAL4sca.PU have missing macrochaetae. The remaining macrochaetae often have morphological defects, including short, burned and misplaced macrochaetae that are apparently coming out of non-socket cells.

      (Mirey et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Statement
      Reference

      RalaG20V.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, enhanceable by Traf4EP578

      (Balakireva et al., 2006)
      Suppressed by
      Statement
      Reference

      RalaG20V.cMa.UAS, Scer\GAL4sca-537.4 has visible phenotype, suppressible by pucE69

      (Balakireva et al., 2006)
      NOT Suppressor of
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      RalaG20V.cMa.UAS, Scer\GAL4sca-537.4 has macrochaeta phenotype, enhanceable by Traf4EP578

      (Balakireva et al., 2006)
      Suppressed by
      Statement
      Reference

      RalaG20V.cMa.UAS, Scer\GAL4sca-537.4 has macrochaeta phenotype, suppressible by pucE69

      (Balakireva et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The lethality caused by expression of RS17A.Scer\UAS under the control of Scer\GAL4GMR.PF is not rescued by co-expression of RalaG20V.cMa.Scer\UAS.

      (Dupuy et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RalG20V
      (Balakireva et al., 2006)
      RalaG20V.cMa.Scer\UAS
      RalaG20V.cMa.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)