FB2025_01 , released February 20, 2025
Allele: Dmel\nAChRα1JF03103
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General Information
Symbol
Dmel\nAChRα1JF03103
Species
D. melanogaster
Name
FlyBase ID
FBal0239603
Feature type
allele
Associated gene
Dmel\nAChRα1
Associated Insertion(s)
Carried in Construct
P{TRiP.JF03103}
Also Known As
UAS-nACHRα1 RNAi, Dα1 RNAi, nAChRα1 RNAi
Key Links
Genomic Maps

Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Perkins et al., 2009)
Mutagen
in vitro construct
(Perkins et al., 2009)
Progenitor genotype
Carried in construct
P{TRiP.JF03103}
Cytology
Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
dsRNA-JF03103
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of nAChRα1JF03103 under the control of Scer\GAL4ple.PF in adults significantly reduces 3 min aversive olfactory memory, compared to controls; there is no effect on sleep, compared to controls.

      (Cervantes-Sandoval et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4qvr.PW/nAChRα1JF03103 is a non-suppressor of abnormal sleep phenotype of qvrEY04063

      (Wu et al., 2014)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of nAChRα1JF03103 under the control of Scer\GAL4qvr.PW does not rescue the reduction in total amount of daily sleep which is seen in qvrEY04063 flies.

      (Wu et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nAChRα1JF03103
      nAChRα1RNAi
      (Cervantes-Sandoval et al., 2017)
      nAcRα-96AaJF03103
      Name Synonyms
      Secondary FlyBase IDs
        References (16)