FB2025_01 , released February 20, 2025
Allele: Dmel\SPEPasteur
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General Information
Symbol
Dmel\SPEPasteur
Species
D. melanogaster
Name
FlyBase ID
FBal0245251
Feature type
allele
Associated gene
Dmel\SPE
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(El Chamy et al., 2008)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Hemizygous SPEPasteur/Df(3R)mbc-R1 or SPEPasteur/Df(3R)mbc-30 animals or flies homozygous for SPEPasteur are highly susceptible to infection with both fungi and Gram-positive bacteria.

      (El Chamy et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT suppressed by
      Statement
      Reference

      SPEPasteur has abnormal immune response | recessive phenotype, non-suppressible by Scer\GAL4Act5C.PI/SPES346G.UAS

      (El Chamy et al., 2008)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The SPEPasteur immune-deficiency phenotype can be rescued by expression of SPEactive.Scer\UAS.T:SV5\V5 driven byScer\GAL4Act5C.PI.

      (El Chamy et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SPEPasteur
      (Fullaondo et al., 2011, El Chamy et al., 2008)
      pstr
      (El Chamy et al., 2008)
      Name Synonyms
      Pasteur
      (El Chamy et al., 2008)
      Secondary FlyBase IDs
        References (2)