FB2025_01 , released February 20, 2025
Allele: Dmel\spdoΔNm.UAS.GFP
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General Information
Symbol
Dmel\spdoΔNm.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0270133
Feature type
allele
Associated gene
Dmel\spdo
Associated Insertion(s)
Carried in Construct
P{UAS-spdo.GFP.ΔNm}
Key Links
Transgenic product class
inframe_deletion
(Song and Lu, 2012)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Song and Lu, 2012)
Mutagen
in vitro construct
(Song and Lu, 2012)
Progenitor genotype
Carried in construct
P{UAS-spdo.GFP.ΔNm}
Cytology
Description

UASt regulatory sequences drive expression of a GFP-tagged spdo mutant polypeptide lacking a short putative PTB domain-interacting motif (YTNPAF) at its N-terminus.

(Song and Lu, 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
spdo
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of spdoΔNm.Scer\UAS.T:Avic\GFP in neuroblasts via Scer\GAL4insc-Mz1407 is insufficient to cause ectopic neuroblast formation.

      (Song and Lu, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of spdoΔNm.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4insc-Mz1407 suppresses the neuroblast-phenotypes resulting from numbScer\UAS.T:Avic\GFP overexpression.

      (Song and Lu, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4insc-Mz1407/spdoΔNm.UAS.GFP rescues spdoG104

      (Song and Lu, 2012)
      Comments

      Expression of spdoΔNm.Scer\UAS.T:Avic\GFP under the control of Scer\GAL4insc-Mz1407 completely rescues the loss of type II neuroblasts in spdoG104 mutants.

      (Song and Lu, 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      spdoΔNm.Scer\UAS.T:Avic\GFP
      spdoΔNm.UAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)