FlyBase Allele Report: Dmel\Ttc1[GL00718]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\Ttc1^GL00718

General Information

Symbol

Dmel\Ttc1^GL00718

Species

D. melanogaster

Name

FlyBase ID

FBal0281105

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{TRiP.GL00718}

Key Links

Genomic Maps

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.GL00718}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Neiswender et al., 2023)

increased size | oogenesis, with Scer\GAL4^{VP16.mat.αTub67C}

(Neiswender et al., 2023)

Phenotype Manifest In

egg | absent, with Scer\GAL4^{VP16.mat.αTub67C}

(Neiswender et al., 2023)

egg chamber, with Scer\GAL4^{VP16.mat.αTub67C}

(Neiswender et al., 2023)

egg chamber, with Scer\GAL4^{VP16.nanos.UTR}

(Neiswender et al., 2023)

embryonic/larval fat body | larval stage, with Scer\GAL4^Cg.PA

(Neiswender et al., 2023)

female fusome | absent, with Scer\GAL4^{VP16.nanos.UTR}

(Neiswender et al., 2023)

mitochondrial crista | absent | oogenesis, with Scer\GAL4^{VP16.mat.αTub67C}

(Neiswender et al., 2023)

mitochondrion | decreased number | larval stage, with Scer\GAL4^Cg.PA

(Neiswender et al., 2023)

mitochondrion | decreased number | oogenesis, with Scer\GAL4^{VP16.mat.αTub67C}

(Neiswender et al., 2023)

mitochondrion | decreased number | oogenesis, with Scer\GAL4^{VP16.nanos.UTR}

(Neiswender et al., 2023)

ovary, with Scer\GAL4^{VP16.nanos.UTR}

(Neiswender et al., 2023)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Ttc1^GL00718 is rescued by Scer\GAL4^{VP16.nanos.UTR}/Ttc1^UAS.EGFP

(Neiswender et al., 2023)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

42763

y¹ sc^* v¹ sev²¹; P{TRiP.GL00718}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

CG14894^GL00718

Ttc1^GL00718

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections