FB2025_01 , released February 20, 2025
Allele: Dmel\Liprin-αUAS.GFP
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General Information
Symbol
Dmel\Liprin-αUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0298833
Feature type
allele
Associated gene
Dmel\Liprin-α
Associated Insertion(s)
Carried in Construct
P{UAS-Liprin-α-GFP}
Key Links
Transgenic product class
wild_type
(Li et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Li et al., 2014)
Mutagen
in vitro construct
(Li et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Liprin-α-GFP}
Cytology
Description

UAS regulatory sequences drive expression of Liprin-α tagged with GFP.

(Li et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Liprin-α
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Liprin-αUAS.GFP/Scer\GAL4Toll-6-D42 is a suppressor of synaptic vesicle phenotype of wrd104

      (Li et al., 2014)

      Liprin-αUAS.GFP/Scer\GAL4Toll-6-D42 is a suppressor of synapse phenotype of wrd104

      (Li et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Neuronal expression of Liprin-αScer\UAS.T:Avic\GFP under the control of Scer\GAL4D42 substantially clears VGlut accumulation at the distal axons of PP2A-B'104 mutants.

      (Li et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU/Liprin-αUAS.GFP rescues Liprin-αF3ex15

      (Li et al., 2014)

      Scer\GAL4elav.PU/Liprin-αUAS.GFP rescues Liprin-αR60

      (Li et al., 2014)
      Comments

      Neuronal expression of Liprin-αScer\UAS.T:Zzzz\TAP under the control of Scer\GAL4elav.PU completely rescues the active zone morphological defects found in Liprin-αR60 mutants.

      Neuronal expression of Liprin-αScer\UAS.T:Zzzz\TAP under the control of Scer\GAL4elav.PU completely rescues the active zone morphological defects found in Liprin-αF3ex15 mutants.

      (Li et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Liprin-αScer\UAS.T:Avic\GFP
      Liprin-αUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (2)