FlyBase Allele Report: Scer\GAL4[loco.PU]

General Information

Symbol

Scer\GAL4^loco.PU

Species

S. cerevisiae

Name

locomotion defects promoter construct of Unknown

FlyBase ID

FBal0318710

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{loco-GAL4.U}

Also Known As

loco-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Dutta et al., 2016)

Progenitor genotype

Carried in construct

P{loco-GAL4.U}

Cytology

Description

loco regulatory sequences control expression of a GAL4 driver.

(FlyBase, 1992-)

Allele components

Component

Use(s)

Regulatory region(s)

loco

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with sws^JF03428

(Sunderhaus et al., 2019)

abnormal neuroanatomy | adult stage, with sws^UAS.cMa

(Dutta et al., 2016)

abnormal neuroanatomy | adult stage | progressive, with sws^GD3277

(Dutta et al., 2016)

abnormal neuroanatomy | adult stage | progressive, with sws^JF03428

(Dutta et al., 2016)

abnormal phototaxis | adult stage, with sws^R133A.UAS

(Dutta et al., 2016)

abnormal phototaxis | adult stage, with sws^S985D.UAS

(Dutta et al., 2016)

abnormal phototaxis | adult stage, with sws^UAS.cMa

(Dutta et al., 2016)

abnormal phototaxis | adult stage | progressive, with sws^GD3277

(Dutta et al., 2016)

abnormal phototaxis | adult stage | progressive, with sws^JF03428

(Dutta et al., 2016)

lethal - all die before end of P-stage, with Hsap\ATXN3^{tr.Q78.UAS.Tag:HA}

(Kretzschmar et al., 2005)

Phenotype Manifest In

adult CNS glial cell | adult stage | progressive, with sws^GD3277

(Dutta et al., 2016)

adult optic chiasma glial cell, with sws^UAS.cMa

(Dutta et al., 2016)

cell body rind of adult lamina | adult stage | progressive, with sws^GD3277

(Dutta et al., 2016)

cell body rind of adult lamina | adult stage | progressive, with sws^JF03428

(Dutta et al., 2016)

first optic chiasma | adult stage, with sws^UAS.cMa

(Dutta et al., 2016)

first optic chiasma | adult stage | progressive, with sws^GD3277

(Dutta et al., 2016)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^R1099Q.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^L524P.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^G578W.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^A1029T.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^UAS.cTa, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, suppressible by Hsap\PNPLA6^T629R.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Scer\GAL4^loco.PU, sws^GD3277 has abnormal neuroanatomy | adult stage | progressive phenotype, suppressible by Mmus\Pnpla6^UAS.cMa, Scer\GAL4^loco.PU

(Dutta et al., 2016)

NOT suppressed by

Statement

Reference

Scer\GAL4^loco.PU, sws^JF03428 has abnormal locomotor behavior | adult stage phenotype, non-suppressible by Hsap\PNPLA6^F2M1.UAS, Scer\GAL4^loco.PU

(Sunderhaus et al., 2019)

Suppressor of

Statement

Reference

Hsap\PNPLA6^R1099Q.UAS, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Hsap\PNPLA6^L524P.UAS, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Hsap\PNPLA6^G578W.UAS, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Hsap\PNPLA6^A1029T.UAS, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Hsap\PNPLA6^UAS.cTa, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Hsap\PNPLA6^T629R.UAS, Scer\GAL4^loco.PU is a suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Mmus\Pnpla6^UAS.cMa, Scer\GAL4^loco.PU is a suppressor of abnormal neuroanatomy | adult stage | progressive phenotype of Scer\GAL4^loco.PU, sws^GD3277

(Dutta et al., 2016)

NOT Suppressor of

Statement

Reference

Hsap\PNPLA6^F2M1.UAS, Scer\GAL4^loco.PU is a non-suppressor of abnormal locomotor behavior | adult stage phenotype of Scer\GAL4^loco.PU, sws^JF03428

(Sunderhaus et al., 2019)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^loco.PU, sws^GD3277 has cell body rind of adult lamina | adult stage | progressive phenotype, suppressible by Mmus\Pnpla6^UAS.cMa, Scer\GAL4^loco.PU

(Dutta et al., 2016)

Suppressor of

Statement

Reference

Mmus\Pnpla6^UAS.cMa, Scer\GAL4^loco.PU is a suppressor of cell body rind of adult lamina | adult stage | progressive phenotype of Scer\GAL4^loco.PU, sws^GD3277

(Dutta et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

sws^UAS.cMa/Scer\GAL4^loco.PU partially rescues sws¹

(Dutta et al., 2016)

sws^UAS.cMa/Scer\GAL4^loco.PU partially rescues sws^GD3277

(Dutta et al., 2016)

sws^R133A.UAS/Scer\GAL4^loco.PU partially rescues sws^GD3277

(Dutta et al., 2016)

Fails to rescue

sws^S985D.UAS/Scer\GAL4^loco.PU fails to rescue sws^GD3277

(Dutta et al., 2016)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^loco.PU

Name Synonyms

locomotion defects promoter construct of Unknown

Secondary FlyBase IDs

References (4)

Report Sections

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