FB2025_01 , released February 20, 2025
Allele: Dmel\HipkUAS.cTa.Tag:HA
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General Information
Symbol
Dmel\HipkUAS.cTa.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0359905
Feature type
allele
Associated gene
Dmel\Hipk
Associated Insertion(s)
Carried in Construct
P{UAS-Hipk.HA.T}
Key Links
Transgenic product class
wild_type
(Tettweiler et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tettweiler et al., 2019)
Mutagen
in vitro construct
(Tettweiler et al., 2019)
Progenitor genotype
Carried in construct
P{UAS-Hipk.HA.T}
Cytology
Description

UASt regulatory sequences drive expression of wild-type Hipk that is tagged with at the N-terminal end with Tag:HA.

(Tettweiler et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hipk
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Wing disc clonal expression of HipkUAS.cTa.Tag:HA under the control of Scer\GAL4Act5C.PI leads to increased eye disc size.

      The expression of HipkUAS.cTa.Tag:HA under the control of Scer\GAL4dpp.blk1 leads to increased mitosis and increased apoptosis in the wing disc, as well as enlargement of the dpp expression domain. Legs are severely deformed.

      (Kinsey et al., 2021)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      HipkUAS.cTa.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (3)