A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Theopold, U., Li, D., Fabbri, M., Scherfer, C., Schmidt, O. (2002). The coagulation of insect hemolymph.  Cell. Molec. Life Sci. 59(2): 363--372. (Export to RIS)
FlyBase ID FBrf0146929
Publication Type Review
PubMed ID 11915949
PubMed Abstract In contrast to both vertebrates and non-insect arthropods, little is known about the coagulation of hemolymph (hemostasis) in insects. We discuss the integration of the hemostatic response with other branches of the insect immune system. We also describe the present stage in the characterization of both soluble and cellular factors that contribute to hemostasis in insects. The factors of the well-characterized clotting cascades of vertebrates, primitive chelicerates and crustaceans are used to assess the implications of sequencing the whole Drosophila genome for searching candidate genes involved in hemostasis. Some striking similarities between blood clotting in vertebrates and the reaction of insect cells involved in hemolymph coagulation have implications for a phylogenetic comparison of hemostasis between divergent animal classes.
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Language of Publication English
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Publication Type Journal
Abbreviation Cell. Molec. Life Sci.
Title Cellular and molecular life sciences. CMLS
Publication Year 1997-
ISBN/ISSN 1420-682X
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